Marian and Michelle Bernard were joined at the abdomen and underwent a delicate seven-hour operation by a team of international surgeons who separated them in Haiti.
It was the first time that an operation of its kind had been performed on the Caribbean island.
An 18-member team of physicians and nurses from Children's Hospital Los Angeles and Keck Medicine of the University of Southern California were all on board to separate the twins.
Led by Dr. Henri Ford, a Haitian surgeon, it was truly an international effort. Ford, moved to Brooklyn, New York in 1972 as a teenager with his family and became an Ivy League-trained pediatric surgeon, now chief of surgery at Children's Hospital Los Angeles.
He opted to take on the surgery to separate the adorable twin girls because he felt it was his duty to help them lead a normal life.
Ford explained that after the devastating earthquake of 2010, he'd gone back to Haiti two or three times to help and was horrified by the carnage wrought by the natural disaster.
He told CBS News: 'I arrived the second day that the airport opened, and pretty much went to work and spent two absolutely grueling weeks, the toughest ones of my life. 'When it came time to leave, I recognized that I couldn't just say, 'Yes, I did my share and it's over.' It wasn't a 'one and done' thing.'
The talented doctor has returned more than 20 times since to provide medical care, to those who fell victim to the earthquake.
In November, Michelle and Marian were born in Port-au-Prince and he became instrumental in their care.
In the spirit of giving back to his homeland, CHLA sent a team of physicians and nurses to the Caribbean nation to perform the rare separation surgery. During the dramatic operation, the medical team used color codes to identify which baby they were working on.
Marian's team was red while Michelle's was yellow. Everything was meticulously planned out and a line was drawn to show the surgeons where to cut the babies apart. The operation went mostly to plan but there was one point when little Michelle's blood pressure dropped.
The development caused concern, but it was soon sorted out when she was given a transfusion and IV fluids. Both twins share a liver and those fluids go from Michelle's blood stream into Marian's.
As soon as the surgeons realized the little girls would pull through, a mini celebration erupted.
Dr. Ford said: 'We now have two babies, two independent living organisms. There is no satisfactory substitute for excellence!'
Meanwhile, the twins' overjoyed parents David and Manousheka expressed their feelings of sheer joy at seeing their daughters separated for the first time since they were born.
They had certainly been through a long and challenging journey. After the earthquake David was badly injured and buried under rubble for seven days before being rescued.
Then they had triplets, Tamar, and her twin sisters.
Their mom, Manousheka told CBS News: 'It's extraordinary to see them lying on their backs.'
She was instrumental in giving the go-ahead for the operation and never wanted them to remain conjoined.
David said: 'Manoushka said if we truly love them we need to give them that chance, to separate them so they can live a full life.'
On Friday, just two weeks after the operation, the healthy girls were discharged from the hospital.
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